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Authors
Affiliations
1 National Centre for Cell Science, Pune University Campus, Pune, Maharashtra, IN
2 Department of Biotechnology, Fergusson College, Pune-411 001, Maharashtra, IN
Source
Nature Environment and Pollution Technology, Vol 10, No 2 (2011), Pagination: 319-326
Abstract
The human body is colonized by an enormous population of bacteria (microbiota) that provides the host with coding capacity and metabolic activities. Among the human gut microbiota are health-promoting indigenous species (probiotic bacteria) that are commonly consumed as live dietary supplements. Recent studies are starting to provide insights into how probiotic bacteria sense and adapt to the gastrointestinal tract environment. In this Review, the application of lactic acid bacteria as probiotics using the well-recognized model probiotic bacterial genera Lactobacillus from gut of silk worm Bombyx mori has been discussed as examples. Recent researches have demonstrated that probiotics can prevent pathogen colonization of the gut and reduce the incidence or relieve the symptoms of various diseases caused by dysregulated immune responses. Therefore, probiotics, through their effects on the host immune system, might ameliorate diseases triggered by disordered immune responses. Caveats remain and, because the beneficial effects of probiotics can vary between strains, the selection of the most suitable ones will be crucial for their use in the prevention or treatment of specific diseases.
Keywords
Bombyx mori, Lactic Acid Bacteria, Bacteriocins, Probiotics.
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